Charged compounds comprising a nucleic acid binding moiety...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2403537

Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.

L'invention concerne des composés chargés comprenant une ou plusieurs zones de charge positive localisés, des compositions contenant lesdits composés, des procédés pour synthétiser lesdits composés, des procédés de criblage de tels composés afin d'identifier ceux qui présentent une activité anti-infectieuse, ainsi que des procédés d'utilisation desdits composés afin de prévenir ou d'inhiber des infections. Ces composés et les compositions les contenant présentent des applications multiples et peuvent même s'utiliser en médecine humaine et animale et dans l'agriculture.

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