Chelants

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 69/48 (2006.01) A61K 47/48 (2006.01) A61K 49/08 (2006.01) A61K 49/12 (2006.01) A61K 51/06 (2006.01)

Patent

CA 2051648

2051648 9012050 PCTABS00002 There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA residues, conjugated to a polyamine backbone molecule, e.g. polylysine. To produce a site-specific polychelate, one or more of the macrocyclic chelant carrying backbone molecules may be conjugated to a site-directed macromolecule, e.g. a protein.

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