C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/101, 167/40,
C07C 229/42 (2006.01) A61K 51/04 (2006.01) C07C 229/16 (2006.01) C07C 233/43 (2006.01) C07C 233/54 (2006.01) C07C 255/30 (2006.01) C07C 331/28 (2006.01) C07F 5/00 (2006.01) G01N 33/534 (2006.01)
Patent
CA 2001765
A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. In addition certain of the chelant- radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.
Frank Richard K.
Garlich Joseph R.
Mcmillan Kenneth
Simon Jaime
Wilson David A.
Dow Global Technologies Inc.
Smart & Biggar
The Dow Chemical Company
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