Chelating agents

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/00 (2006.01) A61K 47/48 (2006.01) A61K 49/04 (2006.01) A61K 51/04 (2006.01) A61K 51/10 (2006.01) C07B 59/00 (2006.01) C07D 273/00 (2006.01) C07D 498/00 (2006.01) C07D 513/08 (2006.01) C07D 515/08 (2006.01) C07F 7/24 (2006.01) C07K 14/00 (2006.01) G01N 33/532 (2006.01) A61K 43/00 (1990.01) A61K 49/02 (1990.01)

Patent

CA 2092434

2092434 9205804 PCTABS00011 Metal chelates and therapeutic or diagnostic conjugates of site-specific compounds, metal chelates, and metal ions are described. The metal chelates consist of at least two molecular components linked together. One molecular component is a chelate having a high affinity for metal ions and a high Ks value. The other molecular component is a chelate having a low Ks value and the ability to undergo rapid metal exchange.

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