Chelating agents of the type xn1s1o for radioactive...

Details Chelating agents of the type xn1s1o for radioactive... Chelating agents of the type xn1s1o for radioactive...

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) C07B 59/00 (2006.01) C07C 323/59 (2006.01) C07C 323/60 (2006.01) C07D 333/34 (2006.01) C07F 13/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 7/64 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2156620

S u m m a r y This invention relates to new bifunctional chelating agents with intermittent chalcogen atoms, pharmaceuticals containing these compounds, their use in radiodiagnostics and radiotherapy, and methods for the production of these compounds. The compound according to the invention has the general formula (I) M - L wherein M represents a radionuclide of Tc or Re and L a ligand of the general formula (II). It was found, surprisingly, that these new, bifunctional chelating agents with intermittent chalcogen atoms and their coupling products with compounds that accumulate specifically are excellently suited for producing radio- pharmaceuticals for diagnostic and therapeutic purposes.

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