Chelating compounds and their use

Details Chelating compounds and their use Chelating compounds and their use

C - Chemistry, Metallurgy

07

C

167/102, 167/260

C07C 237/10 (2006.01) A61K 31/195 (2006.01) A61K 49/06 (2006.01) A61K 51/04 (2006.01) C07C 237/06 (2006.01) C07C 311/41 (2006.01)

Patent

CA 2040204

The present invention provides a chelating compound of the formula: (R-NHOC-CH2)n-A-(CH2COOH)m (I) wherein R is an aromatic ring-containing organic group, A is a residue of an aminopolyacetic acid excluding acetic acid groups (-CH2COOH) therefrom, m is an integer of at least two and n is an integer of 1 or 2, or its salt, which has a specificity to a hepatobiliary system so that a chelate compound formed between said chelating compound and a metallic element through a chelate bond is useful as a diagnostic or therapeutic agent for hepatobiliary organs and tissues.

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