Chemical compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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260/487, 260/466

C07C 69/00 (2006.01) C07D 339/08 (2006.01)

Patent

CA 1111440

ABSTRACT OF THE DISCLOSURE Compounds of the formula (II) are disclosed: Image (II) wherein R1 is a chlorine or bromine atom or a methoxyl, methylthio or C1-4 alkyl group; R2 is a group such that R2C02H is a pharmaceutically acceptable acid of up to 12 carbon atoms; n is 1 or 2; and the dotted line represents a optional double bond. These compounds are useful for their anti-inflammatory properties. Methods of preparation of the compounds are also disclosed.

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