C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2594708
The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof, of the formula (I): which possess B-Raf inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
L'invention concerne des composés chimiques ou des sels de ceux-ci pharmaceutiquement acceptables représentés par la formule (I). Ces composés possèdent une activité inhibitrice de B-Raf et de ce fait, sont utilisés pour leur activité anticancéreuse et dans des traitements du corps humain ou animal. L'invention concerne également des procédés de production desdits composés chimiques, des compositions pharmaceutiques contenant ces composés et leur utilisation pour produire des médicaments possédant un effet anticancéreux chez des animaux à sang chaud, tels que l'homme.
Aquila Brian
Lyne Paul
Pontz Timothy
Astrazeneca Ab
Fetherstonhaugh & Co.
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