C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/437 (2006.01) A61K 31/497 (2006.01) A61K 47/22 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2578746
The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
L'invention concerne de nouveaux composés chimiques présentant des effets protecteurs sur des cellules cibles d'une infection VIH de sorte que ces composés se lient spécifiquement au récepteur de chimiokine et modifient la liaison du ligand naturel ou de la chimiokine naturelle à un récepteur, notamment CXCR4 et/ou CCR5 d'une cellule cible.
Boggs Sharon Davis
Gudmundsson Kristjan
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Smithkline Beecham Corporation
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