C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/10 (2006.01) A61K 31/33 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/445 (2006.01) A61K 31/4523 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01) C07D 277/34 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2729557
The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
L'invention porte sur des composés chimiques de formule (I) R 1 N H S O O et sur leurs sels. Dans certaines exécutions, l'invention porte sur des inhibiteurs ou modulateurs de l'activité ou de la fonction enzymatique des protéines kinases PIM-1 et/ou PIM-2, et/ou PIM-3. Dans d'autres exécutions encore, l'invention porte sur des préparations pharmaceutiques comprenant les composés présentés dans la description, et sur leur utilisation pour la prévention et le traitement d'états et de maladies liés à la kinase PIM, de préférence le cancer.
Dakin Leslie
Dowling James Edward
Lamb Michelle
Read Jon
Su Qibin
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
Chemical compounds 251 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chemical compounds 251, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical compounds 251 will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1608054