C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 271/10 (2006.01) A61K 31/4245 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2651663
Compounds of formula (I), or salts thereof, which inhibit acetyl CoA(acetyl coenzyme A):diacylglycerol acyltransferase (DGAT1) activity are provided, wherein: n is 1, 2 or 3 and each R is independently selected from fluoro, chloro, cyano, methyl, ethyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy and difluoromethoxy; together with processes for their preparation, pharmaceutical compositions containing them and their use as medicaments.
L'invention concerne des composés de formule (I) ou des sels de ceux-ci, qui inhibent l'activité acétyl CoA (acétyl coenzyme A):diacylglycérol acyltransférase (DGAT1), dans laquelle n est 1, 2 ou 3 et chaque R est indépendamment choisi parmi fluoro, chloro, cyano, méthyle, éthyle, méthoxy, éthoxy, trifluorométhyle, trifluorométhoxy et difluorométhoxy ; conjointement avec des procédés pour leur préparation, des compositions pharmaceutiques les contenant et leur utilisation en tant que médicaments.
Johnstone Craig
Plowright Alleyn Thomas
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
Chemical compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chemical compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical compounds will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1501435