C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2632924
The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
L'invention concerne des composés chimiques, ou des sels de ceux-ci pharmaceutiquement acceptables de la formule (I), qui présentent une activité inhibitrice de CSF-1R kinase et qui sont par conséquent utiles de par leur activité anticancéreuse ainsi que dans des méthodes de traitement du corps humain ou animal. L'invention concerne également des procédés de fabrication de ces composés chimiques, des compositions pharmaceutiques les renfermant et leur utilisation dans la fabrication de médicaments à utiliser dans la production d'un effet anticancéreux chez un animal à sang chaud tel que l'humain.
Aquila Brian
Cook Donald
Dakin Leslie
Ioannidis Stephanos
Lyne Paul
Astrazeneca Ab
Fetherstonhaugh & Co.
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