Chemical compounds

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 495/04 (2006.01) A61K 31/407 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2595835

A compound of the formula (1) or a pharmaceutically-acceptable salt: possess glycogen phosphorylase inhibitory activity and accordingly have value in the treatment of disease states associated with increased glycogen phosphorylase activity such as 2 diabetes. Processes for the manufacture of compounds and pharmaceutical compositions containing them are described.

Un composé de formule (1) ou un sel de qualité pharmaceutique dudit composé : présentent une activité inhibitrice de la glycogène phosphorylase et, de ce fait, peuvent être employés dans le traitement d'états pathologiques associés à une augmentation de l'activité de la glycogène phosphorylase, tels que le diabète de type 2. La présente invention décrit en outre des procédés de production desdits composés ainsi que des préparations pharmaceutiques les contenant.

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