Chemical compounds, process for preparing said compounds and...

Details Chemical compounds, process for preparing said compounds and... Chemical compounds, process for preparing said compounds and...

C - Chemistry, Metallurgy

07

D

260/104.5, 260/1

C07D 499/68 (2006.01) C07D 501/24 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1071189

Abstract of the Disclosure p-Trimethylsilyloxy-D-(-)-phenylglycyloxysuccinimide or -phthalimide, process of preparing p-trimethylsilyloxy- D-(-)-phenylglycyloxysuccinimide or -phthalimide by react- ing D-(-)-p-trimethylsilyloxyphenylglycin-N-carboxyanhydride with a N-hydroxyimide, and process for preparing 6-(p- hydroxyphenylglycylamido)-penam or 7-(p-hydroxyphenylglycyl- amido)-cephem compounds by reacting p-trimethylsilyloxy-D- (-)-phenylglycyloxysuccinimide or -phthalimide with a phos- phite amide of an ester of 6-aminopenicillanic acid or of an ester of a 7-amino-3-cephem-4-carboxylic acid in the presence of the hydrochloride of a weak amine. - 1 -

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