Chemical compounds useful in photodynamic therapy and...

Details Chemical compounds useful in photodynamic therapy and... Chemical compounds useful in photodynamic therapy and...

C - Chemistry, Metallurgy

07

F

C07F 5/02 (2006.01) A61K 31/69 (2006.01) A61K 41/00 (2006.01) C09B 57/00 (2006.01)

Patent

CA 2156508

A new group of fluorescent organic compounds having a variety of uses are described. They are especially useful as dye compounds in dye laser systems, and as photochemical agents in the treatment of diseased tissues using photodynamic therapy techniques. The compounds include a tricyclic compound having structure (I). Preferably R1-R5 = R9-R12 = C; R7 = B; R6 and R8 = N; R14 = lower n-alkyl or an electron withdrawing group such as CN-; R16 and R19 are independently selected from the group consisting of lower n-alkyl, a sulfate or an acid or salt thereof, or hydrogen; and R20 = R21 = F. Other compounds include compounds of formula (a), (b), (c), (d), (e).

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