Chemical conjugation of morpholino anthracyclines to antibodies

Details Chemical conjugation of morpholino anthracyclines to antibodies Chemical conjugation of morpholino anthracyclines to antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 47/48 (2006.01) C07H 15/252 (2006.01)

Patent

CA 2048089

ABSTRACT OF THE INVENTION A morpholino anthracycline-linker compound comprising the structure M-L, wherein M is a moxpholino anthracycline compound and L is a linker molecule which is attached to the carbonyl moiety on the C13 substituent of the cyclohexane ring of M.

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