Chemical igf-i formulation for the treatment and prevention...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/30 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2477593

The invention relates to novel, sustained-release IGF-I therapeutic compositions, a preparation and production method thereof and the use of same in the production of medicaments for the treatment and prevention of neurodegenerative diseases such as, among others, Alzheimer's disease or cerebellar ataxia. The inventive compositions take the form of microspheres having a size of less than 5 micrometres, among other characteristics, and subcutaneous implantation capsules.

L'invention concerne de nouvelles compositions thérapeutiques d'administration lente de IGF-I, un procédé de préparation et d'obtention de celles-ci, et leur utilisation dans l'élaboration de médicaments utilisés dans le traitement et la prévention de maladies neurodégénératives telles que, entre autres, la maladie d'Alzheimer ou l'ataxie cérébelleuse. Ces compositions s'adaptent à des microsphères de dimension inférieure à 5 micromètres, entre autres caractéristiques, et à des capsules d'implantation sous-cutanée.

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