Chemical linkers and conjugates thereof

Details Chemical linkers and conjugates thereof Chemical linkers and conjugates thereof

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 5/00 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/103 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2564076

The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine, or disulfide linker. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

L'invention concerne des conjugués médicaments-ligands qui constituent de puissantes cytotoxines. Le médicament est lié au ligand à l'aide d'un bras de liaison peptidyle, hydrazine, ou disulfure. L'invention concerne par ailleurs des compositions qui renferment les conjugués médicaments-ligants, ainsi que des méthodes de traitement qui font intervenir ces conjugués.

Affiliated with

Also associated with

Rating

Chemical linkers and conjugates thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemical linkers and conjugates thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical linkers and conjugates thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1956091