A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 15/28 (2006.01) A61L 15/32 (2006.01) A61L 24/10 (2006.01) A61L 26/00 (2006.01) A61L 27/00 (2006.01) A61L 27/20 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 27/50 (2006.01) A61F 2/00 (2006.01)
Patent
CA 2270599
Biocompatible cross-linked materials, suit- able for use in implants, wound dressings, and blood substitutes, are described. The materials are prepared by cross-linking biological substances, such as collagen, chitosan, or hemoglobin, with genipin, a naturally occurring cross-linking agent. The cross-linking agent has much lower toxic- ity than conventionally used reagents, and the cross-linked products have good thermal and me- chanical stability as well as biocompatibility.
L'invention a trait à des matériaux biocompatibles réticulés, pouvant être utilisés dans des implants, des pansements, et des succédanés du sang. On produit ces matériaux en faisant se réticuler des substances biologiques, notamment le collagène, le chitosane ou l'hémoglobine, au moyen de génipine, un agent de réticulation d'origine naturelle. Cet agent de réticulation est bien moins toxique que les réactifs employés d'ordinaire et les produits réticulés, qui font montre d'une stabilité élevée sur le plan thermique et mécanique, sont également biocompatibles.
Lee Thomas Chau-Jen
Lin Ching-Kuan
Sung Hsing-Wen
Challenge Bioproducts Co. Ltd.
Gowling Lafleur Henderson Llp
LandOfFree
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