Chemical modifications of monomers and oligonucleotides with...

G - Physics – 06 – F

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G06F 3/01 (2006.01) G06F 15/16 (2006.01)

Patent

CA 2737661

The invention features compounds of formula (I) or (II). In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodefi- ciencies and immunosuppression.

La présente invention concerne des composés de formule (I) ou (II). Dans un mode de réalisation, linvention concerne des composés et des procédés pour conjuguer un ligand à un oligonucléotide. Linvention concerne en outre des procédés pour traiter différents troubles et maladies tels que des infections virales, des infections bactériennes, des infections parasitaires, des cancers, des allergies, des maladies auto-immunes, des immunodéficiences et une immunosuppression.

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