Chemical process

C - Chemistry – Metallurgy – 12 – P

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C12P 7/52 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2588591

Enzymatic and chemical processes for the preparation of certain of 3-phenyl-2- arylalkylthiopropionic acid derivatives which have utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance and other manifestations of the metabolic syndrome are described and also certain novel intermediates used in these processes.

L'invention concerne des processus enzymatiques et chimiques intervenant dans la préparation de dérivés d'acide 3-phényl-2-arylalkylthiopropionique qui conviennent pour le traitement d'états pathologiques dont des troubles lipidiques (dyslipidémies), qu'ils soient ou non associés à une résistance à l'insuline, et autres manifestions de syndrome du métabolisme, ainsi que certains intermédiaires nouveaux entrant en jeu dans ces processus.

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