Chemical process

Details Chemical process Chemical process

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) C07D 257/04 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 413/14 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2058899

ABSTRACT CHEMICAL PROCESS The invention provides a novel chemical process for the manufacture of quinoline, pyridine and imidazole derivatives of the formula IV wherein Q, Y1 and Y2 have the various meanings defined herein, and their non-toxic salts, which are angiotensin II inhibitors. The process involves the removal of an electron-deficient phenyl group or a pyridyl or pyrimidyl group from a compound of the formula VI as defined herein. Certain of the intermediates are novel and are provided as a further feature of the invention.

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