C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/08 (2006.01) C07C 69/732 (2006.01) C07D 207/06 (2006.01) C07D 239/88 (2006.01) C07D 403/12 (2006.01) C07D 487/10 (2006.01)
Patent
CA 2667920
The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
La présente invention concerne des procédés chimiques pour la fabrication de certains dérivés de quinazoline ou de sels pharmaceutiquement acceptables de ceux-ci. L'invention concerne également des procédés de fabrication de certains intermédiaires utiles dans la fabrication des dérivés de quinazoline, et des procédés de fabrication des dérivés de quinazoline basés sur lesdits intermédiaires. En particulier, l'invention concerne des procédés chimiques et des intermédiaires utiles dans la fabrication du composé 4-(4-fluoro-2-méthylindol-5-yloxy)-6-méthoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
Arnott Euan Alexander
Crosby John
Evans Matthew Charles
Ford James Gair
Jones Martin Francis
Astrazeneca Ab
Fetherstonhaugh & Co.
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