C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/43 (2006.01) A61K 31/167 (2006.01) A61P 11/08 (2006.01) C07C 231/12 (2006.01)
Patent
CA 2561400
The present invention relates to the preparation of a 2 adrenergic agonist in crystalline salt form. In particular the invention relates to preparation of a crystalline salt of compound (I): in particular a crystalline monohydrochloride salt. The invention also relates to a new crystalline form (polymorph) of the monohydrochloride salt of compound (Ia) and a process for preparing it.
L'invention concerne la préparation d'un agoniste .beta.¿2?-adrénergique sous forme de sel cristallin, et en particulier la préparation d'un sel cristallin du composé (I) : (I), et plus particulièrement d'un monochlorhydrate cristallin. L'invention concerne également une nouvelle forme cristalline (polymorphe) du monochlorhydrate du composé (Ia) et un procédé permettant de préparer celui-ci. ? ¿
Caine Darren Michael
Paternoster Ian Leonard
Shapland Peter David Penberthy
Glaxo Group Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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