A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/00 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/454 (2006.01)
Patent
CA 2284705
The present invention relates to chemically and thermally stable pharmaceutical formulations of the potent antihistamine, norastemizole. The compositions are lactose-free, non-hygroscopic, or anhydrous, or comprise large particles or inertly coated norastemizole, or a pharmaceutically acceptable salt thereof, and are stable and easily manufactured.
La présente invention concerne des formulations chimiquement et thermiquement stables de norastémizole qui est un antihistaminique puissant. Ces compositions, ou certains de leurs sels pharmaceutiquement admis, sont exemptes de lactose, sont non hygroscopiques, sont anhydres, comprennent des grandes particules de norastémizole ou du norastémizole enrobé de façon inerte. Les composés de l'invention sont stables et faciles à fabriquer.
Butler Hal T.
Redmon Martin P.
Wald Stephen A.
Osler Hoskin & Harcourt Llp
Sepracor Inc.
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