Chemically-defined non-polymeric valency platform molecules...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/00 (2006.01) A61K 39/35 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2171434

Chemically-defined, non polymeric valency platform molecules and conjugates comprising chemically-defined valency platform molecules and biological or synthetic molecules including polynucleotide duplexes of at least 20 base pairs that have significant binding activity for human lupus anti-dsDNA autoantibodies.

Molécules plates-formes non polymères à valence, chimiquement définies, et conjugués comprenant lesdites molécules ainsi que des molécules biologiques et synthétiques contenant des duplex polynucléotidiques d'au moins 20 paires de bases qui présentent une activité de liaison appréciable par rapport aux autoanticorps anti-ADN bicaténaire du lupus humain.

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