Chemically-modified human growth hormone conjugates

Details Chemically-modified human growth hormone conjugates Chemically-modified human growth hormone conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 14/61 (2006.01)

Patent

CA 2506821

The present invention provides a chemically modified human Growth Hormone (hGH) prepared by binding a water soluble polymer to the protein. The chemically-modified protein according to the present invention may have a much longer lasting hGH activity than that of the un~modified hGH, enabling reduced dose and scheduling opportunities.

Hormone de croissance humaine (hGH) chimiquement modifiée préparée par liaison d'un polymère hydrosoluble à la protéine. La protéine chimiquement modifiée selon la présente invention peut avoir une activité hGH à durée bien plus longue que celle de la hGH non modifiée, ce qui permet une réduction des doses et une planification de l'administration.

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