Chemically modified hyaluronic acid preparation and method...

Details Chemically modified hyaluronic acid preparation and method... Chemically modified hyaluronic acid preparation and method...

C - Chemistry, Metallurgy

08

B

260/219

C08B 37/08 (2006.01)

Patent

CA 1276143

ABSTRACT OF THE DISCLOSURE Disclosed is hylan, a chemically modified hyaluronic acid preparation characterized by the presence of a small amount (0.005-0.05% by weight) of aldehyde cross-linking groups covalently bonded to the hyaluronic acid molecular chains. AS disclosed is a method of obtaining hylan comprising treating hyaluronic acid in situ in animal tissues containing same with a treatment mixture including a reagent (typically an aldehyde) which is reactive towards hyaluronic acid and the proteins contained in the animal tissue.

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