C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/282, 167/43,
C07D 219/04 (2006.01) C07D 401/12 (2006.01) C09K 11/07 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 1341402
Chemiluminescent acridinium derivative of the formula I (see formula I) in which R1 is hydrogen, an alkyl, alkenyl or alkinyl radical with 1 to 10 carbon atoms or a benzyl or aryl group, R2 and R3 are hydrogen, an alkyl group with 1 to 4 carbon atoms, a substituted or unsubstituted amino group, a carboxyl, C1-C4-alkoxy, cyano or nitro group or halogen, R4 represents a radical in which a sulfonamide group is bonded directly via the nitrogen to the carbonyl group, or is a thioalkyl or thioaryl radical of the formula II - S - X - R5 (II) in which X is a branched or unbranched aliphatic group or an aromatic group, which can also contain heteroatoms, and R5 is a reactive group which can undergo selective bonding under gentle conditions with amino, carboxyl or thiol groups or other functional groups in substances of biological interest, and A~ is an anion which does not impair the chemiluminescence; and for use in luminescence immunoassays.
545036
Kinkel Tonio
Lubbers Henning
Molz Peter
Schnorr Gerd
Skrzipczyk Heinz-Jurgen
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
Siemens Healthcare Diagnostics Products Gmbh
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