Chemiluminescent signal enhancement

Details Chemiluminescent signal enhancement Chemiluminescent signal enhancement

G - Physics

01

N

G01N 33/58 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01)

Patent

CA 2191613

The present invention provides a method for generating an enhanced chemiluminescent signal from an acridinium sulfonamide compound, the method comprising the step of contacting the acridinium sulfonamide compound with a trigger solution in the presence of an enhancer to obtain a chemiluminescent signal which is stronger than would otherwise be generated in the absence of said enhancer. The enhancer comprises at least one member selected from the group consisting of nonionic surfactants, zwitterionic surfactants, and anionic surfactants.

L'invention concerne un procédé servant à générer un signal chimioluminescent amplifié depuis un composé de sulfonamide d'acridinium et consistant à mettre en contact ledit composé avec une solution d'amorçage en présence d'un amplificateur, de manière à obtenir un signal chimioluminescent, dont la force est supérieure à celle d'un signal qui aurait été généré en l'absence dudit amplificateur. Ce dernier comprend au moins un élément sélectionné dans le groupe constitué par des tensio-actifs non ioniques, des tensio-actifs zwitterioniques et des tensio-actifs anioniques.

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