Chemo-enzymatic synthesis of sialylated oligosaccharides

Details Chemo-enzymatic synthesis of sialylated oligosaccharides Chemo-enzymatic synthesis of sialylated oligosaccharides

C - Chemistry, Metallurgy

12

P

C12P 19/00 (2006.01) C07H 15/04 (2006.01) C12P 19/14 (2006.01) C12P 19/18 (2006.01) C12P 19/26 (2006.01) C12P 19/28 (2006.01) C12P 19/44 (2006.01) C12P 19/64 (2006.01)

Patent

CA 2456725

In vitro/cell-free process of preparing a sialylated oligosaccharides are described. The sialylated oligosaccharides include gangliosides. The oligosaccharides linked to various moieties including sphingoids and ceramides. Novel compounds that comprise sphingoid groups are disclosed. The compounds include sialylated oligosaccharides including gangliosides as well as various sphingoids and ceramides.

L'invention se rapporte à un procédé in vitro/acellulaire de préparation d'oligosaccharides sialylés. Ces oligosaccharides sialylés contiennent des gangliosides et sont liés à différents groupes fonctionnels dont les sphingoides et les céramides. L'invention concerne aussi de nouveaux composés qui comprennent des groupes sphingoides. Ces composés comprennent des oligosaccharides sialylés qui contiennent des gangliosides ainsi que plusieurs sphingoides et céramides.

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