Chemo-receptive lipid based membrane transducers

G - Physics – 01 – N

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G01N 27/30 (2006.01) G01N 27/12 (2006.01) G01N 27/49 (2006.01)

Patent

CA 1232946

ABSTRACT OF THE INVENTION A lipid membrane is used as a chemo-receptive transducer in an electrochemical cell, for quantitative and semi-quantitative analysis of chemical test species in an aqueous electrolytic solution. The lipid membrane includes a complexing agent having a high degree of selectivity towards the chemical species. Electrical potential difference is applied across the membrane to produce an analytical signal. From measurements of the analytical signal, a quantitative analysis of the chemical species may be conducted, on a highly selective basis. In one embodiment, the membrane is deposited onto a ion conductive support. In another embodiment, the complexing agent is selective for an inorganic ion and the membrane is consequently ion-selective. This embodiment is useful for forming a gas-sensor electro- chemical cell. In a further embodiment, the complexing agent is a receptor selective for an organic chemical species, and the membrane is organic selective.

488075

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