Chemokine combinations to mobilize progenitor/stem cells

Details Chemokine combinations to mobilize progenitor/stem cells Chemokine combinations to mobilize progenitor/stem cells

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2577046

Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 in combination with the CXCR2 chemokine GRO.beta., including its modified forms, are disclosed.

L'invention concerne des méthodes permettant d'élever le nombre de cellules progénitrices et souches chez des sujets animaux à l'aide de composés qui se fixent au récepteur de chimiokine CXCR4 en combinaison avec la chimiokine CXCR2 GROß, y compris avec ses formes modifiées.

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