Chemokine inhibiting piperazine derivatives and their use to...

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2554974

The present invention relates to piperazine derivatives of formulae Ia, Ib, Ic and Id, where Rla, Rlb, R2, R3, R4, R5, R6, R9, R10 and Y are as defined herein, and their use to treat multiple myeloma.

L'invention porte sur des dérivés de la pipérazine de formules Ia, Ib, Ic et Id, dans lesquelles R?la¿¿, ?R?lb¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?9¿, R?10¿ et Y sont définis dans la description et sur leur utilisation pour traiter les myélomes multiple.

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