Chemokine n-terminal deletion mutations

Details Chemokine n-terminal deletion mutations Chemokine n-terminal deletion mutations

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2222655

The invention relates to mutant chemokines and pharmaceutical compositions thereof, wherein the mutant inhibits the corresponding endogenous chemokine from binding or activating a responsive receptor. The claimed mutant chemokines can be administered to a patient for the treatment or prophylaxis of a chemokine-mediated disease. The invention further relates to isolated DNAs encoding the mutant chemokines, vectors and recombinant host cells containing the same.

L'invention concerne des chémokines mutantes, ainsi que leurs compositions pharmaceutiques, où la mutation empêche la chémokine endogène correspondante de se fixer à un récepteur sensible ou d'activer ledit récepteur. Ces chémokines mutantes peuvent être administrées à un patient, dans le but de réaliser le traitement ou la prophylaxie d'une maladie provoquée par les chémokines. L'invention concerne, de plus, des ADNs isolés codants les chémokines mutantes, ainsi que des vecteurs et des cellules hôtes recombinées les contenant.

Affiliated with

Also associated with

Rating

Chemokine n-terminal deletion mutations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemokine n-terminal deletion mutations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemokine n-terminal deletion mutations will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1941841