Chemokine receptor antagonists and methods of use therefor

Details Chemokine receptor antagonists and methods of use therefor Chemokine receptor antagonists and methods of use therefor

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/4353 (2006.01) A61K 31/438 (2006.01) A61K 31/4427 (2006.01) A61K 31/451 (2006.01) A61K 31/4523 (2006.01) A61K 31/4525 (2006.01) A61K 31/4535 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/527 (2006.01) A61K 31/537 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61K 31/5513 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 19/02

Patent

CA 2467672

Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: formula (1) or physiologically acceptable salt thereof.

L'invention concerne de nouveaux composés, ainsi qu'une méthode de traitement d'une maladie associée à une activation et/ou un recrutement aberrant de leucocytes. Cette méthode consiste à administrer à un sujet nécessitant un traitement une dose efficace d'un composé représenté par la formule (1) ou d'un sel physiologiquement tolérable de celui-ci.

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