Chemokine receptor antagonists and methods of use therefor

Details Chemokine receptor antagonists and methods of use therefor Chemokine receptor antagonists and methods of use therefor

C - Chemistry, Metallurgy

07

D

C07D 491/044 (2006.01) A61K 31/44 (2006.01) A61K 31/55 (2006.01) C07D 221/00 (2006.01) C07D 221/16 (2006.01) C07D 223/00 (2006.01) C07D 313/00 (2006.01) C07D 337/00 (2006.01) C07D 401/06 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2343536

Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by structural formula (I), and physiologically acceptable salts thereof.

L'invention concerne un procédé pour traiter un sujet souffrant d'une maladie associée à la capture et/ou l'activation de leucocytes aberrants. Ce procédé consiste à administrer au sujet une quantité thérapeutiquement efficace d'un composé représenté par la formule structurelle (I) et de sels physiologiquement acceptables de ce dernier.

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