Chemokine receptor binding compounds

Details Chemokine receptor binding compounds Chemokine receptor binding compounds

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4545 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 31/18 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2612105

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).

L'invention concerne des composés de liaison aux récepteurs des chimiokines, des compositions pharmaceutiques et l'utilisation de ceux-ci. Plus précisément, l'invention concerne des modulateurs de l'activité des récepteurs des chimiokines, de préférence, des modulateurs de CCR5. Ces composés possèdent des effets protecteurs contre une infection des cellules cibles par le virus de l'immunodéficience humaine (VIH).

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