C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4545 (2006.01) A61K 38/19 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2517077
Compounds that interact with the CXCR4 receptor are described. The compounds are useful in treating for Example, HIV infection and inflammatory conditions such as rheumatoid arthritis, as well as asthma or cancer, and are useful in methods to elevate progenitor and stem cell counts as well as methods to elevate white blood cell counts.
L'invention concerne des composés qui interagissent avec le récepteur CXCR4. Ces composés sont utiles dans le traitement, par exemple, de l'infection à VIH et d'états inflammatoires tels que la polyarthrite rhumatoïde, l'asthme ou le cancer, et sont utiles dans des procédés visant à augmenter le nombre des cellules souches différenciées ou non, et dans des procédés visant à augmenter le nombre des globules blancs.
Baird Ian
Bridger Gary J.
Chen Gang
Harwig Curtis
Kaller Al
Anormed Inc.
Fetherstonhaugh & Co.
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