Chemoprevention of head and neck squamous cell carcinomas

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/436 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2734828

Disclosed is a method for preventing the development of head and neck squamous cell carcinoma (HNSCC) in a mammal who is at risk for developing such carcinoma comprising administering an effective amount of a mammalian target of rapamycin (mTOR) inhibitor to the mammal. An example of such inhibitor is rapamycin.

La présente invention concerne un procédé pour la prévention du développement d'un carcinome à cellules squameuses de la tête et du cou (HNSCC) chez un mammifère qui présente des risques de développer un tel carcinome. Ce procédé consiste à administrer une quantité efficace d'une cible mammalienne d'un inhibiteur (mTOR) audit mammifère. Un exemple d'un tel inhibiteur est la rapamycine.

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