Chemoprotection using amifostine and related compounds

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01) A61K 31/04 (2006.01) A61K 41/00 (2006.01)

Patent

CA 2446736

The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy in a manner that significantly reduces or decreases the adverse or undesirable side- effects of the compounds as compared with conventional intravenous administration.

La présente invention concerne des méthodes d'administration d'amifostine, de WR-1065, ou d'une combinaison de ceux-ci à des patients soumis à une radiothérapie. Ces méthodes d'administration permettent de réduire sensiblement les effets secondaires indésirables des composés, si l'on par compare avec l'administration intraveineuse classique.

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