Chemorepellant compound

Details Chemorepellant compound Chemorepellant compound

C - Chemistry, Metallurgy

07

C

195/131, 117/156

C07C 59/42 (2006.01) A61K 31/20 (2006.01) A61K 31/23 (2006.01) C07C 69/732 (2006.01)

Patent

CA 1282727

ABSTRACT A chemorepellant compound is disclosed having a general formula Image where R1 is H or an alkyl group in the range C1 to C6, and R2 is H or an appropriate hydroxyl protecting group, and pharmaceutically acceptable salts and esters thereof. A preferred form of the compound where R1 is hydrogen and R2 is hydrogen is made by incubating linoleic acid with soyabean lipoxygenase or with cytosol associated endothelial cell derived lipoxygenase. The chemorepellant compound can be bound to a prosthetic surface via an intermediate linking species such as a protein and studies have shown that platelet adhesion onto in the vicinity of a thrombogenic surface is greatly reduced in comparison to non-chemorepellant coated surfaces.

486737

Affiliated with

Also associated with

Rating

Chemorepellant compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemorepellant compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemorepellant compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1249400