C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) C12N 5/0787 (2010.01) A61K 31/05 (2006.01) A61K 35/74 (2006.01) A61K 35/76 (2006.01) A61K 38/16 (2006.01) A61K 38/57 (2006.01) A61K 45/00 (2006.01) A61P 29/00 (2006.01) C12N 5/00 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2664844
The present invention provides compositions and methods of controlling the direction and/or movement of migratory cells. Specifically, the invention is directed to the identification of novel chemorepellents and unimodal fugetaxins, their agonists and antagonists which alter or affect the movement of cells involved in immune, inflammatory or cancerous phenotypes.
La présente invention concerne des compositions et des procédés permettant de contrôler la direction et/ou le déplacement de cellules migratoires. Spécifiquement, l'invention concerne l'identification de nouveaux répulsifs chimiques et de nouvelles fugetaxines unimodales, leurs agonistes et leurs antagonistes qui modifient ou affectent le déplacement de cellules impliquées dans les phénotypes immunitaire, inflammatoire et cancéreux.
Bhatt Lopa
Goodhew Erica B.
Kang Hyun
Moon Jonathan L.
Rose Stacey L.
Celtaxsys Inc.
Gowling Lafleur Henderson Llp
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