Chewable tablet with effervescent action

Details Chewable tablet with effervescent action Chewable tablet with effervescent action

A - Human Necessities

61

K

A61K 9/46 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2218370

The chewing tablets proposed contain a small amount of effervescent agent (which gives a pleasant fizzy feeling in the mouth), active substances and fillers in amounts chosen so that the tablets will nevertheless dissolve, with the exception of any insoluble or poorly soluble active substances, in 100 ml of water at 15 to 20°C in less that 120, preferably 90, seconds. This is achieved by virtue of the fact that the acid and/or carbonate particles in the effervescent agent are coated with a preferably readily, i.e. rapidly, soluble hydrocolloid and/or the active substance is free of encapsulation agents and the tablet mixture is free of lubricants. Tablet weight is 600 to 1500 mg, preferably only 700 to 1200 mg.

L'invention concerne un comprimé à mâcher contenant une base effervescente en faible quantité (qui produit un picotement agréable dans la bouche), des constituants actifs et des charges dans des proportions telles que le comprimé se dissolve quand même - à l'exception des constituants actifs insolubles ou peu solubles - dans 100 ml d'eau à température comprise entre 15 et 20 DEG C en moins de 120 secondes, de préférence en 90 secondes maximum. Pour ce faire, l'invention propose que les particules d'acide et/ou de carbonate de la base effervescente soient recouvertes d'un hydrocolloïde - de préférence facilement ou rapidement soluble - et/ou que le constituant actif soit exempt de substances d'encapsulage et que le mélange du comprimé soit exempt de lubrifiants. Le comprimé a un poids compris entre 600 et 1500 mg seulement, de préférence entre 700 et 1200 mg.

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