Chimaeric hepadnavirus core antigen proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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530/13, 167/130,

C12N 15/33 (2006.01) A61K 39/12 (2006.01) A61K 39/385 (2006.01) C07K 14/02 (2006.01) C07K 14/08 (2006.01) C07K 14/095 (2006.01) C07K 14/10 (2006.01) C07K 14/15 (2006.01) C07K 14/16 (2006.01) C07K 19/00 (2006.01) C12N 1/20 (2006.01) C12N 5/10 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2025598

Particles, useful as a delivery system for an epitope, are composed of a chimaeric hepadnavirus core antigen protein wherein a foreign amino acid sequence comprising an epitope is inserted in or replaces all or part of the sequence of amino acid residues from 68 to 90 in the case where the core antigen is hepatitis B core antigen or the corresponding amino acid sequence in the case of the core antigen of another hepadnavirus.

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