Chimaeric phages

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 7/00 (2006.01) C07K 14/005 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C40B 30/04 (2006.01) C40B 40/02 (2006.01) C40B 50/06 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2449071

The invention relates to the field of generating helper phages and phage display libraries for the identification of binding molecules. The invention provides chimaeric phages having a coat comprising a protein mixture comprising a fusion protein wherein a proteinaceous molecule is fused to a functional form of a phage coat protein and a mutant form of the phage coat protein, the mutant form being impaired in binding to a host cell receptor. The invention further provides new phage collections, novel helper phages and methods and means for producing chimaeric phages, infectious phages and helper phages according to the invention.

La présente invention concerne le domaine de la production de phages auxiliaires et de banques de présentation de phages permettant d'identifier des molécules de liaison. Cette invention concerne des phages chimériques qui comprennent une couche formée d'un mélange protéique constitué d'une protéine hybride dans laquelle une molécule protéinique est fusionnée à une forme fonctionnelle d'une protéine de couche de phage et à une forme mutante de la protéine de couche de phage, la forme mutante étant altérée et ne pouvant se lier à un récepteur de cellule hôte. Cette invention concerne également de nouvelles collections de phages, de nouveaux phages auxiliaires et des méthodes et des moyens de production de phages chimériques, de phages infectieux et de phages auxiliaires selon l'invention.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Chimaeric phages does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chimaeric phages, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chimaeric phages will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1775093

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.