Chimeric antibodies with new world primate regions

Details Chimeric antibodies with new world primate regions Chimeric antibodies with new world primate regions

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2619245

The present invention provides a chimeric antibody or an antigen-binding portion thereof. The antigen-binding portion comprises at least two complementarity determining regions (CDR) and at least three framework regions, wherein at least one CDR is a New World primate CDR.

La présente invention concerne un anticorps chimérique ou sa partie de liaison à l~antigène. La partie de liaison à l~antigène comprend deux ou plusieurs régions de détermination de complémentarité (CDR) et trois ou plusieurs régions de charpente, selon laquelle un CDR au moins est un CDR de primate du Nouveau Monde.

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