Chimeric gfp-aequorin as bioluminescent ca++ reporters at...

Details Chimeric gfp-aequorin as bioluminescent ca++ reporters at... Chimeric gfp-aequorin as bioluminescent ca++ reporters at...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 49/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C12Q 1/66 (2006.01)

Patent

CA 2411304

A modified bioluminescent system comprising a fluorescent molecule covalently linked with a photoprotein, wherein said link between the two proteins has the function to stabilize the modified bioluminescent system and allowing the transfer of the energy by Chemiluminescence Resonance Energy Transfer (CRET).

L'invention concerne un système bioluminescent modifié comprenant une molécule fluorescente liée par covalence à une photoprotéine. Cette liaison entre les deux protéines a pour fonction de stabiliser le système bioluminescent modifié et de permettre le transfert d'énergie par le système de transfert d'énergie par résonance de chimiluminescence.

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