C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/38 (2006.01) C07K 16/46 (2006.01) G01N 33/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2266339
An immunologic molecule, wherein said immunologic molecule does not compete with monoclonal antibody RWR and is capable of binding to and inhibit both (1) human and nonhuman circulating alpha-2-antiplasmins and (2) human and nonhuman fibrin cross-linked alpha-2-antiplasmins selected from the group consisting of a chimeric antibody, a humanized antibody, and a single chain antibody. The invention further relates to nucleic acid molecules encoding said immunologic molecules.
Molécule immunologique qui n'entre pas en concurrence avec l'anticorps monoclonal RWR, capable de liaison et d'inhibition à la fois sur (1) les alpha-2-antiplasmines circulantes d'origine humaine et non humaine et (2) les alpha-2-antiplasmines à liaisons croisées de fibrine d'origine humaine et non humaine, en effectuant le choix dans le groupe qui comprend un anticorps chimère, un anticorps humanisé et un anticorps à chaîne unique. On décrit aussi des molécules d'acides nucléiques qui codent ce type de molécule immunologique.
Bajorath Jurgen
Harris Linda
Hsu Mei-Yin
Matsueda Gary
Novotny Jiri
Bristol-Myers Squibb Company
Mbm Intellectual Property Law Llp
The General Hospital Corporation
The President And Fellows Of Harvard College
LandOfFree
Chimeric, humanized and single chain antibodies to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chimeric, humanized and single chain antibodies to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chimeric, humanized and single chain antibodies to... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1893539