Chimeric influenza virus-like particles

Details Chimeric influenza virus-like particles Chimeric influenza virus-like particles

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 39/145 (2006.01) A61P 31/14 (2006.01) A61P 37/04 (2006.01) C12N 7/00 (2006.01) C12N 15/09 (2006.01) C07K 14/11 (2006.01) C07K 14/15 (2006.01) C07K 19/00 (2006.01) C12N 9/24 (2006.01)

Patent

CA 2659275

Chimeric Influenza virus-like particles including gag polypeptides are described. Virus-like particles are generated with a gag polypeptide, a neuraminidase polypeptide and optionally a hemagglutinin polypeptide. Preferred methods of generation include expression in insect cells.

L'invention concerne des particules de type de virus grippal chimérique comprenant des polypeptides gag. Des particules de type virus sont générées avec un polypeptide gag, un polypeptide de neuraminidase et éventuellement un polypeptide d'hemagglutinine. Des procédés préférés de génération incluent l'expression dans des cellules d'insectes.

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